choler

Middle English colre, colera, coler "bile (either of the two humors), gastric upset thought to be caused by excess bile," borrowed from Anglo-French & Medieval Latin; Anglo-French colre, colere, borrowed from Medieval Latin colera, cholera "cholera, acute gastroenteritis, bile (by association of the word with Greek cholḗ "gall, bile")," going back to Latin cholera "acute gastroenteritis," borrowed from Greek choléra, of uncertain origin

Note: Greek choléra was linked by ancient and Byzantine medical writers with both cholḗ "gall, bile" and, less plausible derivationally, choládes "guts, entrails." The affix -er- is found in several other names of diseases, as íkteros "icterus, jaundice," hýderos "edema" (compare hydat-, hýdōr "water").